目录产品 » HLA-A*02:01&B2M&CMV pp65 (NLVPMVATV) Monomer, His & Avi, Human
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HLA-A*02:01&B2M&CMV pp65 (NLVPMVATV) Monomer, His & Avi, Human

Human cytomegalovirus (CMV) is one of the major causes of severe complications in immunocompromised patients, such as recipients of hematopoietic cells, solid organ transplantation, and HIV-infected individuals. CMV is also a major pathogen in congenital infection. It can cause life-threatening diseases and severe neurological sequelae in new�born infants. CMV phosphoprotein pp65 is thought to be a major antigen for CMV-specific cellular immunity.
￥3000
Z06554

产品简介
Species Human
Protein Construction
HLA-A*02:01&B2M&CMV pp65 (NLVPMVATV) Monomer [Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and NLVPMVATV peptide]
Accession # A0A140T913(HLA-A*02:01)&P61769(B2M)&NLVPMVATV		 His Avi
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 50.35 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 53-63 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.
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技术背景
Target Background Human cytomegalovirus (CMV) is one of the major causes of severe complications in immunocompromised patients, such as recipients of hematopoietic cells, solid organ transplantation, and HIV-infected individuals. CMV is also a major pathogen in congenital infection. It can cause life-threatening diseases and severe neurological sequelae in new born infants. CMV phosphoprotein pp65 is thought to be a major antigen for CMV-specific cellular immunity.
Synonyms MHC; HLA-A*02:01; CMV pp65
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.