目录产品 » HLA-A*02:01&B2M&AFP (PLFQVPEPV) Monomer, His & Avi, Human
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HLA-A*02:01&B2M&AFP (PLFQVPEPV) Monomer, His & Avi, Human

Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.
￥3000 在线订购包邮(港澳台除外)
Z06552-100

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产品简介
Species Human
Protein Construction
HLA-A*02:01&B2M&AFP (PLFQVPEPV) Monomer [Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and PLFQVPEPV peptide]
Accession # A0A140T913(HLA-A*02:01)&P61769(B2M)&PLFQVPEPV		 His Avi
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 50.4 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 55-60 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.
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图例
HLA-A*02:01&B2M&AFP (PLFQVPEPV) Monomer, His & Avi, Human

The purity of HLA-A*02:01&B2M&AFP (PLFQVPEPV) Monomer, His & Avi, Human is greater than 95% as determined by SEC-HPLC. »

HLA-A*02:01&B2M&AFP (PLFQVPEPV) Monomer, His & Avi, Human

HLA-A*02:01&B2M&AFP (PLFQVPEPV) Monomer, His & Avi, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

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技术背景
Target Background Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.
Synonyms Alpha-fetoprotein; Alpha-1-fetoprotein; Alpha-feto; AFP; HPAFP; AFPD; FETA; MHC
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.