目录产品 » HLA-E*01:03&B2M&EBV LMP1 (GGDPHLPTL) Monomer[Biotin], His & Avi, Human
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HLA-E*01:03&B2M&EBV LMP1 (GGDPHLPTL) Monomer[Biotin], His & Avi, Human

Epstein-Barr virus (EBV)-encoded latent membrane protein 1 (LMP1) is expressed in germinal-center-derived, mononuclear Hodgkin (H) and multinuclear, diagnostic Reed-Sternberg (RS) cells in classical EBV-positive Hodgkin's lymphoma (cHL). LMP1 expression in EBV-negative H-cell lines results in a significantly increased number of RS cells.
￥4900
Z06510-100

产品简介
Species Human
Protein Construction
HLA-E*01:03&B2M&EBV LMP1 (GGDPHLPTL) Monomer [Gly22-Thr302(HLA-E*01:03), Ile21-Met119 (B2M) and GGDPHLPTL peptide]
Accession # P13747(HLA-E*01?)&P61769(B2M)&GGDPHLPTL		 His Avi
N-term C-term
Conjugate Biotin
Purity > 95% as determined by Bis­Tris PAGE
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 50.15 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 53-63 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.
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技术背景
Target Background Epstein-Barr virus (EBV)-encoded latent membrane protein 1 (LMP1) is expressed in germinal-center-derived, mononuclear Hodgkin (H) and multinuclear, diagnostic Reed-Sternberg (RS) cells in classical EBV-positive Hodgkin's lymphoma (cHL). LMP1 expression in EBV-negative H-cell lines results in a significantly increased number of RS cells.
Synonyms EBV LMP1; GGDPHLPTL
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.