Immobilized HLA-A*02:01&B2M&CMVpp65 (NLVPMVATV) Monomer[Biotin], His & Avi, Human, His Tag at 1 μg/ml(100 μl/well) on the streptavidin precoated plate(5 μg/ml). Dose response curve for Anti-B2M Antibody, mFc Tag with the EC50 of 12.1 ng/ml determined by ELISA.
The purity of HLA-A*02:01&B2M&CMVpp65 (NLVPMVATV) Monomer[Biotin], His & Avi, Human is greater than 95% as determined by SEC-HPLC.
HLA-A*02:01&B2M&CMVpp65 (NLVPMVATV) Monomer[Biotin], His & Avi, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
HLA-A*02:01&B2M&CMVpp65 (NLVPMVATV) Monomer[Biotin], His & Avi, Human
Human cytomegalovirus (CMV), a β-herpes virus with a double-stranded DNA, infects a wide variety of cells and establishes latency in the host. CMVpp65, a tegument protein of the herpes virus CMV, is the main viral antigen found in peripheral blood mononuclear cells (PBMCs) after viral infection and may activate cell-mediated immunity, accounting for 70-90% of the cytotoxic CD8+ T cells' (CTLs) response to CMV. Among the pp65-derived CTL epitope peptides, the 9-mer peptide 495NLVPMVATV503 (CMVpp65 495-503 peptide) is the most immunogenic T cell epitope predominantly displayed on HLA-A*02:01, the most common MHC-I allele in the population.
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| ￥4500 | |
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