| Species |
Mouse |
| Protein Construction |
| His |
PKM2 (Pro2-Pro531)_x000D_
Accession # NP_001240812.1 |
| N-term |
C-term |
|
| Purity |
> 95% as determined by Bis-Tris PAGE |
| Endotoxin Level |
Less than 1EU per μg by the LAL method. |
| Expression System |
Baculovirus-Insect Cells |
| Theoretical Molecular Weight |
58.95 kDa |
| Apparent Molecular Weight |
The protein has a predicted MW of 58.95 kDa same as Bis-Tris PAGE result. |
| Formulation |
Lyophilized from 0.22μm filtered solution in 20mM Tris, 500mM NaCl (pH 7.0). |
| Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Storage & Stability |
Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles. |
| Target Background |
Pyruvate kinase M2 (PKM2), a key rate-limiting enzyme of glycolysis, is a critical regulator in tumor metabolism. PKM2 has been demonstrated to overexpressed in various cancers and promoted proliferation and metastasis of tumor cells. |
| Synonyms |
Pkm; Pk3; Pykm; Pk-2; Pk-3 |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.
