Species |
Mouse |
Protein Construction |
Complement Factor I (Arg19-Val603)_x000D_ Accession # Q61129 |
His |
N-term |
C-term |
|
Purity |
> 90% as determined by BisTris PAGE > 90% as determined by HPLC |
Endotoxin Level |
Less than 1EU per μg by the LAL method. |
Expression System |
HEK293 |
Theoretical Molecular Weight |
66.39 kDa |
Apparent Molecular Weight |
Due to autocatalytic cleavage and glycosylation, the protein migrates to 80-100 kDa on Bis-Tris PAGE result. |
Formulation |
Lyophilized from 0.22μm filtered solution in 50mM Tris, 150mM NaCl (pH 8.0). |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Storage & Stability |
Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles. |
Target Background |
Complement factor I (CFI) is a serine protease which plays a key role in the modulation of complement system and the induced-fit factor responsible for controlling the complement-mediated processes. |
Synonyms |
C3B/C4B inactivator; CFI; IF; C3BINA; FIC3b-INA; I factor (complement); KAF |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.