目录产品 » CA9/Carbonic Anhydrase IX, His, Mouse

CA9/Carbonic Anhydrase IX, His, Mouse

CA9 is a member of the carbonic anhydrases' family, that is often expressed in cancer cells under hypoxic condition. CA9 expression potentially contributes to the regulation of cancer cell differentiation and mediates tumour-associated genes and signalling pathways, including apoptosis, hypoxia, G2M checkpoint, PI3K/AKR/mTOR signalling and TGF-beta signalling pathways.
¥3600
Z06041-100

Species Mouse
Protein Construction
CA9/Carbonic Anhydrase IX (Gln32-Asp390)_x000D_
Accession # NP_647466.2
His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 43.12 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 50-53 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.
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CA9/Carbonic Anhydrase IX, His, Mouse

The purity of CA9/Carbonic Anhydrase IX, His, Mouse is greater than 95% as determined by SEC-HPLC. »

CA9/Carbonic Anhydrase IX, His, Mouse

CA9/Carbonic Anhydrase IX, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

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Target Background CA9 is a member of the carbonic anhydrases' family, that is often expressed in cancer cells under hypoxic condition. CA9 expression potentially contributes to the regulation of cancer cell differentiation and mediates tumour-associated genes and signalling pathways, including apoptosis, hypoxia, G2M checkpoint, PI3K/AKR/mTOR signalling and TGF-beta signalling pathways.
Synonyms CA9; CAIX; CA-IX; EC 4.2.1.1; G250; MN; P54/58N; PMW1; RCC
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.