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APOE/Apolipo E hFc Chimera, Mouse

Apolipoprotein E (apoE) is a lipid carrier in both the peripheral and the central nervous systems. Lipid-loaded apoE lipoprotein particles bind to several cell surface receptors to support membrane homeostasis and injury repair in the brain. Considering prevalence and relative risk magnitude, the ε4 allele of the APOE gene is the strongest genetic risk factor for late-onset Alzheimer's disease (AD).
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Z06009-100

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产品简介
Species Mouse
Protein Construction
APOE/Apolipoprotein E (Glu19-Gln311)_x000D_
Accession # P08226		 hFc
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 60.7 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 62-66 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in 20mM PB, 150mM NaCl (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.
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图例
APOE/Apolipo E HFc Chimera, Mouse

The purity of APOE/Apolipo E hFc Chimera, Mouse is greater than 90% as determined by SEC-HPLC. »

APOE/Apolipo E HFc Chimera, Mouse

APOE/Apolipo E hFc Chimera, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

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技术背景
Target Background Apolipoprotein E (apoE) is a lipid carrier in both the peripheral and the central nervous systems. Lipid-loaded apoE lipoprotein particles bind to several cell surface receptors to support membrane homeostasis and injury repair in the brain. Considering prevalence and relative risk magnitude, the ε4 allele of the APOE gene is the strongest genetic risk factor for late-onset Alzheimer's disease (AD).
Synonyms Apolipoprotein E; Apo-E; APOE; apolipo E
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.