| ￥3500 | |
| Z05929-100 | |
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| Species | Human | ||||
| Protein Construction |
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| Purity | > 95% as determined by BisTris PAGE | ||||
| Endotoxin Level | Less than 1 EU per μg by the LAL method. | ||||
| Biological Activity | Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch. | ||||
| Expression System | HEK293 | ||||
| Theoretical Molecular Weight | 41.69 kDa | ||||
| Apparent Molecular Weight | Due to furin cleavage site, the protein migrates to 38-42 kDa based on Bis-Tris PAGE result. | ||||
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). | ||||
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. | ||||
| Storage & Stability | Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles. |
Loaded TSLP hFc Chimera, Human, hFc Tag on ProA-Biosensor can bind Human TSLPR, His Tag with an affinity constant of 82.50 nM as determined in BLI assay (Gator® Prime). »
Immobilized TSLP hFc Chimera, Human, hFc Tag at 5 μg/ml (100 μI/well) on the plate. Dose response curve for Human TSLPR, His Tag with the EC50 of 0.50 μg/ml determined by ELISA. »
Immobilized TSLP hFc Chimera, Human, hFc Tag at 2 μg/ml (100 μI/well) on the plate. Dose response curve for Biotinylated Anti-TSLP Antibody, hFc Tag with the EC50 of 87.0ng/ml determined by ELISA. »
The purity of TSLP hFc Chimera, Human is greater than 95% as determined by SEC-HPLC. »
TSLP hFc Chimera, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »
| Target Background | Thymic Stromal Lymphopoietin (TSLP) was originally identified as an activity from the conditioned medium of a mouse thymic stromal cell line that promoted the development of B cells. Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c dendritic cells. Can induce allergic inflammation by directly activating mast cells. |
| Synonyms | thymic stromal lymphopoietin; TSLP |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.
