| Species |
Human |
| Protein Construction |
THSD7A (Ala48–Trp1607)_x000D_
Accession # Q9UPZ6 |
His |
| N-term |
C-term |
|
| Purity |
> 95% as determined by BisTris PAGE
> 95% as determined by HPLC |
| Endotoxin Level |
Less than 1EU per μg by the LAL method. |
| Expression System |
HEK293 |
| Theoretical Molecular Weight |
176.22 kDa |
| Apparent Molecular Weight |
Due to glycosylation, the protein migrates to 180-240 kDa based on Bis-Tris PAGE result. |
| Formulation |
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). |
| Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Storage & Stability |
Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles. |
| Target Background |
Thrombospondin type I domain-containing 7A (THSD7A), is a specific autoantigen of adult idiopathic membranous nephropathy (IMN), whose circulating antibody (THSD7A-AB) represents a promising biomarker for diagnosis of IMN. |
| Synonyms |
Thrombospondin type-1 domain-containing protein 7A;Gm837;KIAA0960;thrombospondin,type I,domain containing 7A |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.
