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PLA2G7, His, Human

Endogenous PLA2G7 transcription levels were found to be significantly lower in vascular related cell lines than in the other cell lines. Luciferase reporter gene assays indicated that gene activity was significantly enhanced by PLA2G7 promoter fragment. LA2G7 transcription was found to be up-regulated with the treatment of DAC. The 17-β-estradiol was found to down-regulate PLA2G7 transcription in all the cell lines.
￥3300
Z05757-100

产品简介
Species Human
Protein Construction
PLA2G7 (Phe22-Asn441)_x000D_
Accession # Q13093		 His
N-term C-term
Purity > 95% as determined by Bis-Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 48.9 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 49-60 kDa based on Bis-Tris PAGE result.
Formulation Supplied as 0.22μm filtered solution in 50mM NaAc, 150mM NaCl, 10% Glycerol (pH 5.0).
Concentration Verified by one or more methods from 0.64mg/ml A280/Bioactivity/BCA/Bradford.
Storage & Stability This product remains stable for 6 months at -80°C or below. Avoid repeated freeze-thaw cycles.
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技术背景
Target Background Endogenous PLA2G7 transcription levels were found to be significantly lower in vascular related cell lines than in the other cell lines. Luciferase reporter gene assays indicated that gene activity was significantly enhanced by PLA2G7 promoter fragment. LA2G7 transcription was found to be up-regulated with the treatment of DAC. The 17-β-estradiol was found to down-regulate PLA2G7 transcription in all the cell lines.
Synonyms LDL-PLA2; PAFAD; PAFAH
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.