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PLA2G1B, His, Human

Phospholipase A2 (PLA2) plays crucial roles in diverse cellular responses, including phospholipid digestion and metabolism, host defense and signal transduction. PLA2 provides precursors for generation of eicosanoids, such as prostaglandins (PGs) and leukotrienes (LTs), when the cleaved fatty acid is arachidonic acid, platelet-activating factor (PAF) when the sn-1 position of the phosphatidylcholine contains an alkyl ether linkage and some bioactive lysophospholipids, such as lysophosphatidic acid (lysoPA).
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产品简介
Species Human
Protein Construction
PLA2G1B (Ala23-Ser148)_x000D_
Accession # P04054		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 15.23 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 18-23 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in 10mM Tris, 5mM CaCl2 (pH 8.0).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.
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图例
PLA2G1B, His, Human

The purity of PLA2G1B, His, Human is greater than 95% as determined by SEC-HPLC. »

PLA2G1B, His, Human

PLA2G1B, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

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技术背景
Target Background Phospholipase A2 (PLA2) plays crucial roles in diverse cellular responses, including phospholipid digestion and metabolism, host defense and signal transduction. PLA2 provides precursors for generation of eicosanoids, such as prostaglandins (PGs) and leukotrienes (LTs), when the cleaved fatty acid is arachidonic acid, platelet-activating factor (PAF) when the sn-1 position of the phosphatidylcholine contains an alkyl ether linkage and some bioactive lysophospholipids, such as lysophosphatidic acid (lysoPA).
Synonyms Phospholipase A2; PLA2G1B; PLA2; PLA2A; PLA2AMGC119834
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.