Species |
Human |
Protein Construction |
His |
Latent PDGFD (Arg19-Arg370)_x000D_ Accession # Q9GZP0-1 |
N-term |
C-term |
|
Purity |
> 95% as determined by Bis-Tris PAGE |
Endotoxin Level |
Less than 1EU per μg by the LAL method. |
Expression System |
HEK293 |
Theoretical Molecular Weight |
41.82 kDa |
Apparent Molecular Weight |
Due to glycosylation, the protein migrates to 50-65 kDa based on Bis-Tris PAGE result. |
Formulation |
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Storage & Stability |
Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles. |
Target Background |
Platelet‑derived growth factor D (PDGF‑D) is a new member of the PDGF family that binds the PDGFR‑β homodimer. PDGF‑D promotes the angiogenic capacity of EPCs, including proliferation, migration, adhesion and tube formation, and thereby contributes to angiogenesis. |
Synonyms |
PDGF-D; SCDGF-B; IEGF; SCDGFB |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.