| ￥3800 | |
| Z05707-100 | |
|
|
|
|
|
|
|
|
|
| Species | Human | ||||
| Protein Construction |
|
||||
| Purity | > 95% as determined by BisTris PAGE | ||||
| Endotoxin Level | Less than 1EU per μg by the LAL method. | ||||
| Biological Activity | Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch. | ||||
| Expression System | HEK293 | ||||
| Theoretical Molecular Weight | 74.56 kDa | ||||
| Apparent Molecular Weight | Due to glycosylation, the protein migrates to 80-110 kDa based on Bis-Tris PAGE result. | ||||
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). | ||||
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. | ||||
| Storage & Stability | Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles. |
Immobilized NPR1/NPRA mFc Chimera, Human, mFc Tag at 5 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-NPR1 Antibody, hFc Tag with the EC50 of 40.0 ng/ml determined by ELISA. »
The purity of NPR1/NPRA mFc Chimera, Human is greater than 90% as determined by SEC-HPLC. »
NPR1/NPRA mFc Chimera, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »
Loaded NPR1/NPRA mFc Chimera, Human, mFc Tag on Anti-Mouse IgG Fc-Biosensor can bind Anti-NPR1 Antibody, hFc-Avi Tag with an affinity constant of 1.20 nM as determined in BLI assay (Gator® Prime). »
Immobilized NPR1/NPRA mFc Chimera, Human, mFc Tag at 5 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-NPR1 Antibody, hFc Tag with the EC50 of 40.0ng/ml determined by ELISA. »
| Target Background | NPR1 (natriuretic peptide receptor 1), a receptor of ANP (atrial natriuretic peptide) whitch acting through NPR1, provokes hypotension. NPR1 was abundantly expressed in endothelial cells and smooth muscle cells of small arteries and arterioles. NPR1 plays a crucial role in ANP-mediated blood pressure regulation, presumably by a mechanism that is RGS2-dependent in the acute phase and RGS2-independent in the chronic phase. |
| Synonyms | ANP-A; ANPR-A; NPR-A; GC-A; ANPRA |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.
