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IL-7 R alpha&TSLPR, His, Human

IL-7R alpha & TSLPR is an heterodimeric receptor, with TSLP as the ligand, which initiates downstream signaling pathways upon binding to TSLP and subsequently participates in thymus development and immune cell generation. Among them, IL-7R alpha is a component of both the IL-7 and TSLP receptors.
¥3800
Z05513-100

Species Human
Protein Construction
IL-7 R alpha&TSLPR (Glu21-Asp239 (IL-7 R alpha) and Gln23-Lys231 (TSLPR))_x000D_
Accession # P16871-1(IL-7 R alpha)&Q9HC73-1(TSLPR)
His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 31.18 kDa (IL-7 R alpha) and 29.03 kDa (TSLPR)
Apparent Molecular Weight Due to glycosylation, the protein migrates to 58-68 kDa (IL-7 R alpha) and 50-58 kDa (TSLPR) based on Bis-Tris PAGE result.
Formulation Supplied as 0.22 μm filtered solution in PBS (pH 7.4).
Concentration Verified by one or more methods from 0.64mg/ml A280/Bioactivity/BCA/Bradford.
Storage & Stability This product remains stable for 6 months at -80°C or below. Avoid repeated freeze-thaw cycles.
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Target Background IL-7R alpha & TSLPR is an heterodimeric receptor, with TSLP as the ligand, which initiates downstream signaling pathways upon binding to TSLP and subsequently participates in thymus development and immune cell generation. Among them, IL-7R alpha is a component of both the IL-7 and TSLP receptors.
Synonyms IL7Ra; CD127; TSLP R; CRLF2; IL-XR; ILXR; p2RY8; TSLPR; CRL2; CRLF2Y
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.