| ￥2300 | |
| Z05512-100 | |
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| Species | Human | |
| Protein Construction |
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| Purity | > 95% as determined by BisTris PAGE | |
| Endotoxin Level | Less than 0.01EU per μg by the LAL method. | |
| Biological Activity | Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch. | |
| Expression System | E.coli | |
| Theoretical Molecular Weight | 17.5 kDa | |
| Apparent Molecular Weight | The protein has a predicted MW of 17.5 kDa same as Bis-Tris PAGE result. | |
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS (pH 8.0). | |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. | |
| Storage & Stability | Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles. |
Measured in a cell proliferation assay using murine 2E8 cells. The ED50 for this effect is 0.1 - 0.5 ng/mL (QC tested). »
Immobilized IL-7, Human, No Tag at 2 μg/ml (100 μI/well) on the plate. Dose response curve for Human IL-7R alpha, hFc Tag with the EC50 of 14.4ng/ml determined by ELISA. »
The purity of IL-7, Human is greater than 95% as determined by SEC-HPLC. »
IL-7, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »
Human IL-7 R alpha, His Tag captured on CM5 Chip via anti-his antibody can bind IL-7, Human, No Tag with an affinity constant of 7.15 nM as determined in SPR assay (Biacore T200). »
| Target Background | Interleukin-7 (IL7) plays a nonredundant role in T cell survival and homeostasis, which is illustrated in the severe T cell lymphopenia of IL7-deficient mice, or demonstrated in animals or humans that lack expression of either the IL7Rα or γ c chain, the two subunits that constitute the functional IL7 receptor. |
| Synonyms | IL7; Interleukin-7; IL-7; Lymphopoietin-1; PBGF |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.
