| ￥2300 | |
| Z05509-100 | |
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| Species | Human | |
| Protein Construction |
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| Purity | > 95% as determined by BisTris PAGE | |
| Endotoxin Level | Less than 0.05EU per μg by the LAL method. | |
| Biological Activity | Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch. | |
| Expression System | E.coli | |
| Theoretical Molecular Weight | 20.8 kDa | |
| Apparent Molecular Weight | The protein has a predicted 20.8 kDa same as Bis-Tris PAGE result. | |
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). | |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. | |
| Storage & Stability | Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles. |
Loaded Human IL-6 R alpha, hFc Tag on ProA-Biosensor can bind IL-6, Human, No Tag with an affinity constant of 16.50 nM as determined in BLI assay (Gator® Prime). »
Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells. The ED50 for this effect is 0.1 - 0.8 ng/mL. (QC Test) »
Immobilized IL-6, Human, No Tag at 2 μg/ml (100 μI/well) on the plate. Dose response curve for Human IL-6 R alpha, hFc Tag with the EC50 of 4.8ng/ml determined by ELISA. »
The purity of IL-6, Human is greater than 90% as determined by SEC-HPLC. »
IL-6, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »
Human IL-6 R alpha, His Tag captured on CM5 Chip via anti-his antibody can bind IL-6, Human, No Tag with an affinity constant of 0.22 nM as determined in SPR assay (Biacore T200). »
| Target Background | IL-6 (Interleukin-6) is a pleiotropic cytokine that acts in the acute phase reaction, inflammation, hematopoiesis, bone metabolism, and cancer progression.Interleukin 6 has been shown to interact with interleukin-6 receptor and glycoprotein. |
| Synonyms | IFN-beta-2; IL6; IL-6; BSF-2; CDF; MGI-2A; Interleukin-6; HSF; IFNB2; HGF;IFN-β-2 |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.
