| ￥4900 | |
| Z05480-100 | |
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| Species | Human | ||||||
| Protein Construction |
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| Purity |
> 95% as determined by BisTris PAGE > 95% as determined by HPLC |
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| Endotoxin Level | Less than 1EU per μg by the LAL method. | ||||||
| Biological Activity | Measured by its binding ability in a functional ELISA. Immobilized Human IL22, His Tag at 2μg/ml (100μl/well) on the plate can bind IL-22R alpha 1&IL-10R beta hFc Chimera, Avi, Human. Test result was comparable to standard batch. | ||||||
| Expression System | HEK293 | ||||||
| Theoretical Molecular Weight | 52.07 kDa (IL-22R alpha 1) and 48.85 kDa (IL-10R beta) | ||||||
| Apparent Molecular Weight | Due to glycosylation, the protein migrates to 68-75 kDa based on Bis-Tris PAGE result. | ||||||
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). | ||||||
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. | ||||||
| Storage & Stability | Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles. |
| Target Background | IL-22Rα1 & IL-10Rβ are receptors for IL-22 and IL-10, mediate the activation of JAK-STAT, MAPK and other signaling pathways, and participate in the process of many inflammatory diseases. IL-22 Rα1 contains cytoplasmic motifs for interactions with signal transduction molecules, but formation of ternary complexes with IL10 Rβ or IL20 Rβ and the respective ligands is required for signal transduction. |
| Synonyms | IL-22R alpha 1; IL-10R beta; IL-22Rα1&IL-10Rβ |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.
