| ￥1300 | |
| Z05470-100 | |
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| Species | Human | |
| Protein Construction |
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| Purity | > 95% as determined by BisTris PAGE | |
| Endotoxin Level | Less than 0.01EU per μg by the LAL method. | |
| Biological Activity | Measured in a cell proliferation assay using CTLL‑2 mouse cytotoxic T cells. Test result was comparable to standard batch. | |
| Expression System | E.coli | |
| Theoretical Molecular Weight | 15.5 kDa | |
| Apparent Molecular Weight | The protein has a predicted 15.5 kDa same as Bis-Tris PAGE result. | |
| Formulation | Lyophilized from 0.22μm filtered solution in 100mM Acetic Acid. | |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in 100mM Acetic Acid. | |
| Storage & Stability | Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles. |
Measured in a cell proliferation assay using CTLL‑2 mouse cytotoxic T cells. The ED50 for this effect is 0.5-2 ng/mL (QC Test). »
The purity of IL-2, Human is greater than 95% as determined by SEC-HPLC. »
IL-2, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »
Human IL-2 R alpha, His Tag captured on CM5 Chip via anti-his antibody can bind IL-2, Human, No Tag with an affinity constant of 16.82 nM as determined in SPR assay (Biacore T200). »
Human IL-2 R beta, His Tag captured on CM5 Chip via Anti-His Antibody can bind IL-2, Human, No Tag with an affinity constant of 0.25μM as determined in SPR assay (Biacore T200). »
Human IL-2 R beta&IL-2 R gamma, hFc Tag captured on CM5 Chip via Protein A can bind IL-2, Human, No Tag with an affinity constant of 0.114 nM as determined in SPR assay (Biacore T200). »
| Target Background | Interleukin-2 (IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system. It is a 15,5 - 16 kDa protein that regulates the activities of white blood cells (leukocytes, often lymphocytes) that are responsible for immunity. IL-2 has essential roles in key functions of the immune system, tolerance and immunity, primarily via its direct effects on T cells. |
| Synonyms | IL2; T-cell growth factor; TCGF; Aldesleukin |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.
