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IgG4 Fc, Human

It is known as a IgG4-related disease and its differentiation is based on the analysis of IgG4 levels in the affected tissues. The IgG4-related disease is considered to be a generalized pathological process involving a wide spectrum of various disorders that may affect distant organs.
￥800 在线订购包邮(港澳台除外)
Z05416-100

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产品简介
Species Human
Protein Construction
IgG4 Fc (Glu99-Gly326)
Accession # P01861
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Loaded Human FcRn, His Tag on Anti-His-Biosensor can bind IgG4 Fc, Human,No Tag in BLI assay (Gator® Prime). Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 25.8 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 30-35 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.
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图例
IgG4 Fc, Human

The purity of IgG4 Fc, Human is greater than 95% as determined by SEC-HPLC. »

IgG4 Fc, Human

IgG4 Fc, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

IgG4 Fc, Human

Human FcRn, His Tag captured on CM5 Chip via Anti-His Antibody can bind IgG4 Fc, Human, No Tag with an affinity constant of 1.365 μM as determined in SPR assay (Biacore T200). »

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技术背景
Target Background It is known as a IgG4-related disease and its differentiation is based on the analysis of IgG4 levels in the affected tissues. The IgG4-related disease is considered to be a generalized pathological process involving a wide spectrum of various disorders that may affect distant organs.
Synonyms IGHG4
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.