目录产品 » gp130/CD130/IL-6 R beta, His, Human
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gp130/CD130/IL-6 R beta, His, Human

gp130 is a common signal transducing component of the functional receptor complexes for the interleukin (IL)-6 family of cytokines, ie, IL-6, IL-11, leukemia inhibitory factor (LIF), oncostatin M, ciliary neurotrophic factor, and cardiotrophin-1. These cytokines exhibit pleiotropic biological activities in, for instance, immune, hematopoietic, and neural systems, and function in a redundant manner owing to the shared usage of gp130.
￥2600
Z05364

产品简介
Species Human
Protein Construction
gp130/CD130/IL-6 R beta (Glu23-Glu619)_x000D_
Accession # P40189-1		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE
> 95%  as determined by HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Immobilized Human IL­6 R alpha, hFc Tag at 2μg/ml (100μl/well) on the Human IL­6, No Tag precoated plate (5μg/ml) can bind gp130/CD130/IL-6 R beta, His, Human. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 68.94 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 80-110 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.
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技术背景
Target Background gp130 is a common signal transducing component of the functional receptor complexes for the interleukin (IL)-6 family of cytokines, ie, IL-6, IL-11, leukemia inhibitory factor (LIF), oncostatin M, ciliary neurotrophic factor, and cardiotrophin-1. These cytokines exhibit pleiotropic biological activities in, for instance, immune, hematopoietic, and neural systems, and function in a redundant manner owing to the shared usage of gp130.
Synonyms gp130; CD130; IL-6 R beta; IL-6R-beta; IL-6RB; CDw130; IL6ST
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.