| ￥3800 | |
| Z05344-100 | |
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| Species | Human | |
| Protein Construction |
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| Purity | > 95% as determined by BisTris PAGE | |
| Endotoxin Level | Less than 0.1EU per μg by the LAL method. | |
| Biological Activity | Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch. | |
| Expression System | E.coli | |
| Theoretical Molecular Weight | 15.06 kDa | |
| Apparent Molecular Weight | The protein has a predicted MW of 15.06 kDa same as Bis-Tris PAGE result. | |
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). | |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. | |
| Storage & Stability | Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles. |
Measured in a cell proliferation assay using SH‑SY5Y human neuroblastoma cells. The ED50 for this effect is 2‑12 ng/mL in the presence of Recombinant Human GFR alpha ‑1/GDNF R alpha ‑1 Fc Chimera. (QC Test) »
Immobilized GDNF, Human, No Tag at 1 μg/ml (100 μI/well) on the plate. Dose response curve for Human GFR alpha 1, His Tag with the EC50 of 2.6ng/ml determined by ELISA. »
The purity of GDNF, Human is greater than 95% as determined by SEC-HPLC. »
GDNF, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »
| Target Background | Glial cell line-derived neurotrophic factor (GDNF) is a 134 amino acid protein belonging in the GDNF family ligands (GFLs). GDNF was originally isolated from rat glial cell lines and identified as a neurotrophic factor with the ability to promote dopamine uptake within midbrain dopaminergic neurons. |
| Synonyms | Glial cell line-derived neurotrophic factor; hGDNF; Astrocyte-derived trophic factor (ATF) |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.
