目录产品 » Fc gamma RI/CD64, His & Avi, Human
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Fc gamma RI/CD64, His & Avi, Human

The Fc gamma Rs have been divided into three classes based on close relationships in their extracellular domains; these groups are designated Fc gamma RI (also known as CD64), Fc gamma RII (CD32), and Fc gamma RIII (CD16). Each group may be encoded by multiple genes and exist in different isoforms depending on species and cell type.
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Z05275-100

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产品简介
Species Human
Protein Construction
Fc gamma RI/CD64 (Gln16-Pro288)
Accession # P12314-1		 His Avi
N-term C-term
Purity > 95% as determined by Bis-Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Fc gamma RI/CD64, His & Avi, Human captured on CM5 Chip via anti­his antibody can bind Trastuzumab in SPR assay (Biacore T200). Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 33.5 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 50-70 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.
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图例
Fc Gamma RI/CD64, His & Avi, Human

Fc gamma RI/CD64, His & Avi, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

Fc Gamma RI/CD64, His & Avi, Human

Fc gamma RI/CD64, His & Avi, Human, His Tag captured on CM5 Chip via anti-his antibody can bind Trastuzumab with an affinity constant of 5.25 nM as determined in SPR assay (Biacore T200). »

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技术背景
Target Background The Fc gamma Rs have been divided into three classes based on close relationships in their extracellular domains; these groups are designated Fc gamma RI (also known as CD64), Fc gamma RII (CD32), and Fc gamma RIII (CD16). Each group may be encoded by multiple genes and exist in different isoforms depending on species and cell type.
Synonyms CD64; CD64a; Fc gamma RI; FCG1; Fc-gamma RIA; FCGR1; FcgRI; FCRI; FcRIA; FLJ18345; FCGR1A; IGFR1; Fcr; Fcgr; FCE1A; FcERI; FcγRI; Fc γRI; Fcγ RI; Fc γ RI
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.