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EphA7, His, Human

Ephrin receptor A7 (EphA7) is a member of the Eph receptor family. It is widely involved in signal transduction between cells, regulates cell proliferation and differentiation, and participates in developing neural tubes and brain. In addition, EphA7 also has a dual role of tumor promoter and tumor suppressor.
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产品简介
Species Human
Protein Construction
EphA7 (Gln28-Val555)
Accession # NP_004431.1		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 60.13 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 65-70 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.
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图例
EphA7, His, Human

Immobilized EphA7, His, Human, His Tag at 2 μg/ml (100 μl/well) on the plate. Dose response curve for Human Ephrin-A4, hFc Tag with the EC50 of 3.5ng/ml determined by ELISA. »

EphA7, His, Human

The purity of EphA7, His, Human is greater than 95% as determined by SEC-HPLC. »

EphA7, His, Human

EphA7, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

EphA7, His, Human

EphA7, His, Human, His Tag immobilized on CM5 Chip can bind Human Ephrin-A4, His Tag with an affinity constant of 0.113 μM as determined in SPR assay (Biacore T200). »

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技术背景
Target Background Ephrin receptor A7 (EphA7) is a member of the Eph receptor family. It is widely involved in signal transduction between cells, regulates cell proliferation and differentiation, and participates in developing neural tubes and brain. In addition, EphA7 also has a dual role of tumor promoter and tumor suppressor.
Synonyms EHK-3; EHK3; EK11; hEK11; EPHA7;
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.