| Species |
Human |
| Protein Construction |
Complement Factor I (Lys19-Val583)
Accession # P05156 |
His |
| N-term |
C-term |
|
| Purity |
> 95% as determined by BisTris PAGE
> 95% as determined by HPLC |
| Endotoxin Level |
Less than 1EU per μg by the LAL method. |
| Expression System |
HEK293 |
| Theoretical Molecular Weight |
64.58 kDa |
| Apparent Molecular Weight |
Due to enzyme lysis and glycosylation, the protein migrates to 75-95 kDa based on Bis-Tris PAGE result. |
| Formulation |
Lyophilized from 0.22μm filtered solution in 20mM Tris, 150mM NaCl (pH 8.0). |
| Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Storage & Stability |
Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles. |
| Target Background |
Complement factor I (CFI) is a serine protease which plays a key role in the modulation of complement system and the induced-fit factor responsible for controlling the complement-mediated processes. |
| Synonyms |
EC:3.4.21.45; C3B/C4B inactivator; CFI; IF; C3BINA; FIC3b-INA; I factor (complement); KAF |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.
