| Species |
Human |
| Protein Construction |
CDH6/Cadherin 6 (Thr19-Ala615)_x000D_
Accession # P55285-1 |
His |
| N-term |
C-term |
|
| Purity |
> 95% as determined by BisTris PAGE
> 95% as determined by HPLC |
| Endotoxin Level |
Less than 1 EU per μg by the LAL method. |
| Biological Activity |
Measured by its binding ability in a functional ELISA. Immobilized AntiCDH6 antibody, hFc Tag at 5μg/ml (100μl/well) on the plate can bind CDH6/Cadherin6, His, Human. Test result was comparable to standard batch. |
| Expression System |
HEK293 |
| Theoretical Molecular Weight |
67.48 kDa |
| Apparent Molecular Weight |
Due to glycosylation, the protein migrates to 75-95 kDa based on Bis-Tris PAGE result. |
| Formulation |
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). |
| Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Storage & Stability |
Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles. |
| Target Background |
Cadherin 6 (CDH6) is an adhesion molecule localizing to the endometrial luminal epithelial cell surface in the mid-secretory/receptive phase and knockdown of CDH6 in the Ishikawa cells (receptive endometrial epithelial cell line) compromises cell integrity. |
| Synonyms |
Cadherin-6; Cadherin6; K-cadherin; CDH6; CAD6; KCAD; |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.
