| Species |
Human |
| Protein Construction |
| His |
CCL7/MCP3 (Gln24-Leu99)
Accession # P80098 |
| N-term |
C-term |
|
| Purity |
> 95% as determined by BisTris PAGE
> 95% as determined by HPLC |
| Endotoxin Level |
Less than 1EU per μg by the LAL method. |
| Expression System |
E.coli |
| Theoretical Molecular Weight |
10.05 kDa |
| Apparent Molecular Weight |
The protein migrates to 14-17 kDa based on Bis-Tris PAGE result. |
| Formulation |
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). |
| Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Storage & Stability |
Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles. |
| Target Background |
Chemokine C-C motif ligand 7 (CCL7), a member of CC chemokine subfamily, is known to promote the recruitment of many innate immune cell types including monocytes and neutrophils to sites of bacterial and viral infection and eosinophils and basophils to sites of allergic inflammation. CCL7 upregulation has been associated with many inflammatory settings including infection, cardiovascular disease, and the tumor microenvironment. |
| Synonyms |
C-C motif chemokine 7; CCL7; NC28; MCP-3; MCP3; SCYA6; SCYA7; FIC; MARC |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.
