Immobilized ANGPT2/Angiopoietin-2, His & Avi, Human, His Tag at 2 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-ANGPT2 Antibody, hFc Tag with the EC50 of 17.8 ng/ml determined by ELISA.

ANGPT2/Angiopoietin-2, His & Avi, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Human TIE2, His Tag immobilized on CM5 Chip can bind ANGPT2/Angiopoietin-2, His & Avi, Human, His Tag with an affinity constant of 2.38 μM as determined in SPR assay (Biacore T200).

ANGPT2/Angiopoietin-2, His & Avi, Human

Angiopoietin-2 (Ang-2; also ANGPT2) is a secreted glycoprotein that plays a complex role in angiogenesis and inflammation. Mature Ang-2 is 478 amino acids in length.Ang2 is widely expressed during development, but it is restricted postnatally to highly angiogenic tissues such as the placenta, ovaries, and uterus. It is particularly abundant in vascular endothelial cells (EC) where it is stored in intracellular Weibel Palade bodies..

产品编号	Z05018
规格	100 μg 500 μg 大单询价
数量
价格	￥2200


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产品简介

Species

Human

Protein Construction

Avi	His	NGPT2/Angiopoietin-2 (Lys275-Phe496) Accession # O15123-1
N-term		C-term

Purity

> 95% as determined by Bis-Tris PAGE

Endotoxin Level

Less than 1EU per μg by the LAL method.

Biological Activity

Measured by its binding ability in a functional ELISA. Immobilized ANGPT2/Angiopoietin-2, His & Avi, Human at 2μg/ml (100μl/well) can bind AntiANGPT2 Antibody, hFc Tag. Test result was comparable to standard batch

Expression System

HEK293

Theoretical Molecular Weight

28.4 kDa

Apparent Molecular Weight

Due to glycosylation, the protein migrates to 30-35 kDa based on Bis-Tris PAGE result.

Formulation

Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).

Reconstitution

Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.

Storage & Stability

Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

图例

ANGPT2/Angiopoietin-2, His & Avi, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Human TIE2, His Tag immobilized on CM5 Chip can bind ANGPT2/Angiopoietin-2, His & Avi, Human, His Tag with an affinity constant of 2.38 μM as determined in SPR assay (Biacore T200).

技术背景

Target Background

Synonyms

AGPT2; ANG2; ANG-2; angiopoietin 2; Angiopoietin-2; angiopoietin-2a; angiopoietin-2B; angiopoitin 2; ANGPT2; Tie2-ligand

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.

ANGPT2/Angiopoietin-2, His & Avi, Human

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