| ￥1600 | |
| Z04989-100 | |
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| Species | Human/Cynomolgus | ||||
| Protein Construction |
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| Purity | > 95% as determined by BisTris PAGE | ||||
| Endotoxin Level | Less than 1EU per μg by the LAL method. | ||||
| Biological Activity | Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch. | ||||
| Expression System | HEK293 | ||||
| Theoretical Molecular Weight | 39.32 kDa | ||||
| Apparent Molecular Weight | Due to glycosylation, the protein migrates to 50-70 kDa based on Bis-Tris PAGE result. | ||||
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). | ||||
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. | ||||
| Storage & Stability | Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles. |
Immobilized Human Activin A, No Tag at 5 μg/ml(100 μI/well) on the plate. Dose response curve for Activin RIIB/ACVR2B mFc Chimera, Human/Cynomolgus, mFc Tag with the EC50 of 21.3ng/ml determined by ELISA. »
Immobilized Activin RIIB/ACVR2B mFc Chimera, Human/Cynomolgus, mFc Tag at 0.5 μg/ml (100 μI/well) on the plate. Dose response curve for Anti-Activin RIIB Antibody, hFc Tag with the EC50 of 6.9ng/ml determined by ELISA. »
Immobilized Human/Mouse/Rat GDF-8, No Tag at 1 μg/ml (100 μI/well) on the plate. Dose response curve for Activin RIIB/ACVR2B mFc Chimera, Human/Cynomolgus, mFc Tag with the EC50 of 20.8ng/ml determined by ELISA. »
Activin RIIB/ACVR2B mFc Chimera, Human/Cynomolgus on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »
| Target Background | ActRIIB (activin receptor type-2B) is an activin receptor subtype constitutively expressed in the whole body, playing a role in cellular proliferation, differentiation, and metabolism. For its various physiological activities, ActRIIB interacts with activin and multiple other ligands including myostatin (MSTN), growth differentiation factor 11 (GDF11), and bone morphogenetic protein 9 (BMP9). |
| Synonyms | Activin receptor type-2B; ACVR2B; Activin RIIB |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.
