目录产品 » Transthyretin/Prealbumin, His, Cynomolgus

Transthyretin/Prealbumin, His, Cynomolgus

Transthyretin is a highly conserved homotetrameric protein, mainly synthetized by the liver and the choroid plexus of brain. The carrier role of TTR is well-known; however, many other functions have emerged, namely in the nervous system. TTR aggregates are responsible for many amyloidosis such as familial amyloidotic polyneuropathy and cardiomyopathy. Normal TTR can also aggregate and deposit in the heart of old people and in preeclampsia placental tissue.
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Z04934

Species Cynomolgus
Protein Construction
His Transthyretin/Prealbumin (Gly21-Glu147)
Accession # Q8HXW1
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 14.80 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 16-20 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.
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Transthyretin/Prealbumin, His, Cynomolgus

The purity of Transthyretin/Prealbumin, His, Cynomolgus is greater than 95% as determined by SEC-HPLC. »

Transthyretin/Prealbumin, His, Cynomolgus

Transthyretin/Prealbumin, His, Cynomolgus on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

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Target Background Transthyretin is a highly conserved homotetrameric protein, mainly synthetized by the liver and the choroid plexus of brain. The carrier role of TTR is well-known; however, many other functions have emerged, namely in the nervous system. TTR aggregates are responsible for many amyloidosis such as familial amyloidotic polyneuropathy and cardiomyopathy. Normal TTR can also aggregate and deposit in the heart of old people and in preeclampsia placental tissue.
Synonyms Transthyretin; ATTR; Prealbumin; TBPA; TTR; PALB; CTS; CTS1; HsT2651; HEL111
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.