目录产品 » Transferrin R/CD71, His, Cynomolgus
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Transferrin R/CD71, His, Cynomolgus

The transferrin receptor (CD71) is known as a receptor for IgA1 on mesangial cells. The transcript and protein expression of glomerular CD71 was determined by real-time polymerase chain reaction and immunohistochemistry. Human mesangial cells (HMCs) were treated with sera from IgAN patients and expression levels of CD71 and inflammatory cytokine markers were compared according to disease status.
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产品简介
Species Cynomolgus
Protein Construction
His Transferrin R/CD71 (Cys89-Phe760)
Accession # XP_005545315.1
N-term C-term
Purity > 90% as determined by Bis-Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 76.3 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 78-80 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.
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图例
Transferrin R/CD71, His, Cynomolgus

Transferrin R/CD71, His, Cynomolgus on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

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技术背景
Target Background The transferrin receptor (CD71) is known as a receptor for IgA1 on mesangial cells. The transcript and protein expression of glomerular CD71 was determined by real-time polymerase chain reaction and immunohistochemistry. Human mesangial cells (HMCs) were treated with sera from IgAN patients and expression levels of CD71 and inflammatory cytokine markers were compared according to disease status.
Synonyms TR; TfR1; CD71; sTfR; T9; p90; TFRC; TFR
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.