目录产品 » LILRB2/CD85d/ILT4, His, Cynomolgus
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LILRB2/CD85d/ILT4, His, Cynomolgus

The immunoglobulin-like transcript (ILT) comprise a family of activating and inhibitory type immunoreceptors whose genes are located in the same locus that encodes killer cell Ig-like receptors (KIR). ILT4, also known as LIR-2 and LILRB2, is a type I transmembrane protein expressed primarily on monocytes and dendritic cells (DC). LILRB2 is a receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles.
￥3500
Z04859-100

产品简介
Species Cynomolgus
Protein Construction
LILRB2/CD85d/ILT4 (Gly24-Arg457)
Accession # XP_015297203.1		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 48.2 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.
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图例
LILRB2/CD85d/ILT4, His, Cynomolgus

The purity of LILRB2/CD85d/ILT4, His, Cynomolgus is greater than 95% as determined by SEC-HPLC. »

LILRB2/CD85d/ILT4, His, Cynomolgus

LILRB2/CD85d/ILT4, His, Cynomolgus on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

LILRB2/CD85d/ILT4, His, Cynomolgus

LILRB2/CD85d/ILT4, His, Cynomolgus, His Tag immobilized on CM5 Chip can bind Cynomolgus HLA-G Complex Tetramer, His Tag with an affinity constant of 852 nM as determined in SPR assay (Biacore T200). »

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技术背景
Target Background The immunoglobulin-like transcript (ILT) comprise a family of activating and inhibitory type immunoreceptors whose genes are located in the same locus that encodes killer cell Ig-like receptors (KIR). ILT4, also known as LIR-2 and LILRB2, is a type I transmembrane protein expressed primarily on monocytes and dendritic cells (DC). LILRB2 is a receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles.
Synonyms CD85d; ILT4; ILT-4; ILT4CD85d; LILRB2; LIR2; MIR10
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.