The purity of Fc gamma RIII/CD16[Biotin], His & Avi, MouseI is greater than 95% as determined by SEC-HPLC.
Fc gamma RIII/CD16[Biotin], His & Avi, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
OKT3 captured on CM5 Chip via Protein A can bind Fc gamma RIII/CD16[Biotin], His & Avi, Mouse, His Tag with an affinity constant of 0.164 μM as determined in SPR assay (Biacore T200).
Fc gamma RIII/CD16[Biotin], His & Avi, Mouse
Immunoglobulin G (IgG) Fc receptors play a critical role in linking IgG antibody-mediated immune responses with cellular effector functions. A high resolution map of the binding site on human IgG1 for human Fc gamma RI, Fc gamma RIIA, Fc gamma RIIB, Fc gamma RIIIA, and FcRn receptors has been determined.A common set of IgG1 residues is involved in binding to all Fc gamma R; Fc gamma RII and Fc gamma RIII also utilize residues outside this common set.
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