| Species |
Human |
| Protein Construction |
| Avi |
His |
IL-21 (Gln32-Ser162)
Accession # Q9HBE4-1 |
| N-term |
|
C-term |
|
| Conjugate |
Biotin |
| Purity |
> 95% as determined by Bis-Tris PAGE |
| Endotoxin Level |
Less than 1EU per μg by the LAL method. |
| Biological Activity |
Measured by its binding ability in a functional ELISA. Immobilized Human IL21R, hFc Tag at 1μg/ml (100μl/Well) on the plate can bind IL-21[Biotin], His & Avi, Human. Test result was comparable to standard batch |
| Expression System |
E.coli |
| Theoretical Molecular Weight |
18.30 kDa |
| Apparent Molecular Weight |
The protein has a predicted MW of 18.30 kDa same as Bis-Tris PAGE result. |
| Formulation |
Lyophilized from 0.22 μm filtered solution in 20mM NaAc, 500mM NaCl (pH 5.5). |
| Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in 20mM NaAc, 500mM NaCl (pH 5.5). |
| Storage & Stability |
Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles. |
| Target Background |
Interleukin-21 (IL-21), produced predominantly by CD4 T cells and natural killer T (NKT) cells, is a newly discovered member of the common γ-chain family of cytokines. It has been implicated in many immunological processes and has been linked to autoimmune diseases, allergies and other inflammatory diseases. |
| Synonyms |
Interleukin-21; IL-21; Za11; CVID11 |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.
