| ￥6600 | |
| Z04455-100 | |
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| Species | Human | ||||
| Protein Construction |
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| Conjugate | Biotin | ||||
| Purity |
> 95% as determined by BisTris PAGE > 90% as determined by HPLC |
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| Endotoxin Level | Less than 1EU per μg by the LAL method. | ||||
| Biological Activity | Measured by its binding ability in a functional ELISA. Immobilized AntiFcRH5 Antibody, hFc Tag at 5μg/ml (100μl/well) on the plate can bind FcRH5/FcRL5[Biotin], His, Human. Test result was comparable to standard batch. | ||||
| Expression System | HEK293 | ||||
| Theoretical Molecular Weight | 92.38 kDa | ||||
| Apparent Molecular Weight | Due to glycosylation, the protein migrates to 100-120 kDa based on Bis-Tris PAGE result. | ||||
| Formulation | Lyophilized from 0.22μm filtered solution in PBS, 100mM Arginine (pH 7.4). | ||||
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. | ||||
| Storage & Stability | Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles. |
Immobilized Anti-FcRH5 Antibody, hFc Tag at 5 μg/ml (100 μl/well) on the plate. Dose response curve for FcRH5/FcRL5[Biotin], His, Human, His Tag with the EC50 of 35.6 ng/ml determined by ELISA. »
The purity of FcRH5/FcRL5[Biotin], His, Human is greater than 90% as determined by SEC-HPLC. »
FcRH5/FcRL5[Biotin], His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »
| Target Background | FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE), a potent anti-mitotic agent. |
| Synonyms | FcR-like protein 5; FcRH5; FcRL5; BXMAS1; BXMAS1MGC119592; CD307; CD307e; DKFZp667E2019; DKFZp667F216; FCRH5MGC119593; FLJ00333; FLJ00397; IFGP5; IRTA2 |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.
