Immobilized ANGPT2/Angiopoietin-2[Biotin], His & Avi, Human, His Tag at 1 μg/ml (100 μl/Well) on streptavidin(5 μg/ml) precoated plate. Dose response curve for Anti-ANGPT2 Antibody, hFc Tag with the EC50 of 3.7 ng/ml determined by ELISA.
ANGPT2/Angiopoietin-2[Biotin], His & Avi, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
Human TIE2, His Tag immobilized on CM5 Chip can bind ANGPT2/Angiopoietin-2[Biotin], His & Avi, Human, His Tag with an affinity constant of 2.93 μM as determined in SPR assay (Biacore T200).
ANGPT2/Angiopoietin-2[Biotin], His & Avi, Human
Angiopoietin-2 (Ang-2; also ANGPT2) is a secreted glycoprotein that plays a complex role in angiogenesis and inflammation. Mature Ang-2 is 478 amino acids in length.Ang2 is widely expressed during development, but it is restricted postnatally to highly angiogenic tissues such as the placenta, ovaries, and uterus. It is particularly abundant in vascular endothelial cells (EC) where it is stored in intracellular Weibel Palade bodies.
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