The purity of Fc gamma RIII/CD16[Biotin], His & Avi, Cynomolgus is greater than 95% as determined by SEC-HPLC.
Fc gamma RIII/CD16[Biotin], His & Avi, Cynomolgus on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
Fc gamma RIII/CD16[Biotin], His & Avi, Cynomolgus, His Tag captured on CM5 Chip via Anti-His Antibody can bind Rituximab with an affinity constant of 0.15 μM as determined in SPR assay (Biacore T200) (QC Test).
Fc gamma RIII/CD16[Biotin], His & Avi, Cynomolgus
Immunoglobulin G (IgG) Fc receptors play a critical role in linking IgG antibody-mediated immune responses with cellular effector functions. A high resolution map of the binding site on human IgG1 for human Fc gamma RI, Fc gamma RIIA, Fc gamma RIIB, Fc gamma RIIIA, and FcRn receptors has been determined.A common set of IgG1 residues is involved in binding to all Fc gamma R; Fc gamma RII and Fc gamma RIII also utilize residues outside this common set.
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