Species |
Mouse |
Protein Construction |
Siglec-2/CD22 (Ser22–Arg702) Accession # P35329-1 |
His |
N-term |
C-term |
|
Purity |
> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC |
Endotoxin Level |
Less than 1EU per μg by the LAL method. |
Expression System |
HEK293 |
Theoretical Molecular Weight |
80.25 kDa |
Apparent Molecular Weight |
Due to glycosylation, the protein migrates to 110-115 kDa based on Bis-Tris PAGE result. |
Formulation |
Lyophilized from a 0.22 μm filtered solution in PBS, (pH 7.4). |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Storage & Stability |
Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles. |

The purity of Siglec-2/CD22, His, Mouse is greater than 95% as determined by SEC-HPLC.

Siglec-2/CD22, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
Target Background |
CD22, or cluster of differentiation-22, is a molecule belonging to the SIGLEC family of lectins. It is found on the surface of mature B cells and to a lesser extent on some immature B cells. CD22 a member of the immunoglobulin superfamily. CD22 functions as an inhibitory receptor for B cell receptor (BCR) signaling. It is also involved in the B cell trafficking to Peyer's patches in mice. |
Synonyms |
CD22 molecule; CD22; Siglec-2; B-cell receptor CD22; BL-CAM; SIGLEC2; SIGLEC2FLJ22814 |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.