The purity of CD8 alpha/CD8A, His, Mouse is greater than 95% as determined by SEC-HPLC.

CD8 alpha/CD8A, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

CD8 alpha/CD8A, His, Mouse

CD8 alpha enhances the responses of antigen-specific CTL activated through TCR through binding MHC class I, favoring lipid raft partitioning of TCR, and inducing intracellular signaling. CD8 alpha is also found on dendritic cells and rat macrophages, but whether CD8 alpha enhances responses of a partner receptor, like TCR, to activate these cells is not known.

产品编号	Z04331
规格	100 μg 500 μg 大单询价
数量
价格	￥3800


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产品简介

Species

Mouse

Protein Construction

CD8 alpha/CD8A (Lys28-Tyr196） Accession # P01731-1	His
N-term	C-term

Purity

> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC

Endotoxin Level

Less than 1EU per μg by the LAL method.

Expression System

HEK293

Theoretical Molecular Weight

20 kDa

Apparent Molecular Weight

Due to glycosylation, the protein migrates to 32-42 kDa based on Bis-Tris PAGE result.

Formulation

Lyophilized from a 0.22 μm filtered solution in PBS, (pH 7.4).

Reconstitution

Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.

Storage & Stability

Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

图例

The purity of CD8 alpha/CD8A, His, Mouse is greater than 95% as determined by SEC-HPLC.

CD8 alpha/CD8A, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

技术背景

Target Background	CD8 alpha enhances the responses of antigen-specific CTL activated through TCR through binding MHC class I, favoring lipid raft partitioning of TCR, and inducing intracellular signaling. CD8 alpha is also found on dendritic cells and rat macrophages, but whether CD8 alpha enhances responses of a partner receptor, like TCR, to activate these cells is not known.
Synonyms	CD8a; Lyt-2; CD8; Leu2; MAL; p32; CD8a molecule; OKT8 T-cell antigen

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.