| ￥3000 | |
| Z04306 | |
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| Species | Mouse | ||||
| Protein Construction |
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| Purity |
> 95% as determined by BisTris PAGE > 95% as determined by HPLC |
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| Endotoxin Level | Less than 1EU per μg by the LAL method. | ||||
| Biological Activity | Measured by its binding ability in a functional ELISA. Immobilized Mouse CD27, mFc Tag at 2μg/ml (100μl/Well) on the plate can bind CD27 Ligand/CD70 hFc Chimera, Mouse. Test result was comparable to standard batch. | ||||
| Expression System | HEK293 | ||||
| Theoretical Molecular Weight | 43.41 kDa | ||||
| Apparent Molecular Weight | Due to glycosylation, the protein migrates to 55-60 kDa based on Bis-Tris PAGE result. | ||||
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 6.2). | ||||
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. | ||||
| Storage & Stability | Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles. |
Immobilized Mouse CD27, mFc Tag at 2 μg/ml (100 μL/well) on the plate. Dose response curve for CD27 Ligand/CD70 hFc Chimera, Mouse, hFc Tag with the EC50 of 20.4 ng/ml determined by ELISA. »
The purity of CD27 Ligand/CD70 hFc Chimera, Mouse is greater than 95% as determined by SEC-HPLC. »
CD27 Ligand/CD70 hFc Chimera, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »
| Target Background | CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7. CD70 is a cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells. |
| Synonyms | CD70 molecule; CD70; TNFSF7; CD27 Ligand; CD27-L; CD27LG; Ki-24 antigen; TNFSF7G |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.
