目录产品 » CD93/C1q R1, His, Human
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CD93/C1q R1, His, Human

CD93 has been shown critical roles in inflammatory and immune diseases. CD93 silencing increased IL-6 and TSLP, but not IL-33 levels in culture supernatants. HDM-induced asthma mice showed significant airway hyperresponsiveness and inflammation with Th2 cytokine activation, along with decreased CD93 expression in bronchial epithelial cells and lung homogenates but increased serum CD93 levels.
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Z04234-100

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产品简介
Species Human
Protein Construction
CD93/C1q R1 (Thr22-Lys580)
Accession # Q9NPY3		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA.Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 59.4 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 95-110 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.
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图例
CD93/C1q R1, His, Human

Immobilized CD93/C1q R1, His, Human, His Tag (100 μl/well) on the plate. Dose response curve for Human IGFBP7, hFc Tag with the EC50 of 0.67 μg/ml determined by ELISA. »

CD93/C1q R1, His, Human

The purity of CD93/C1q R1, His, Human is greater than 95% as determined by SEC-HPLC. »

CD93/C1q R1, His, Human

CD93/C1q R1, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

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技术背景
Target Background CD93 has been shown critical roles in inflammatory and immune diseases. CD93 silencing increased IL-6 and TSLP, but not IL-33 levels in culture supernatants. HDM-induced asthma mice showed significant airway hyperresponsiveness and inflammation with Th2 cytokine activation, along with decreased CD93 expression in bronchial epithelial cells and lung homogenates but increased serum CD93 levels.
Synonyms C1q/MBL/SPA receptor; C1qR; C1qR(p); C1qRp; CDw93; CD93; C1QR1; MXRA4; ECSM3; dJ737E23.1
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.