Immobilized CD8 alpha&beta Heterodimer, His & Flag, Human, His Tag at 2 μg/ml (100 μL/well) on the plate. Dose response curve for Anti-CD8 Antibody, hFc Tag with the EC50 of 11.3 ng/ml determined by ELISA.
The purity of CD8 alpha&beta Heterodimer, His & Flag, Humanr is greater than 95% as determined by SEC-HPLC.
CD8 alpha&beta Heterodimer, His & Flag, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
CD8 alpha&beta Heterodimer, His & Flag, Human
CD8 alpha&beta (CD8αβ) is a heterodimeric form of CD8. CD8α is required for surface expression of CD8β. The extracellular IgV-like domain of CD8α interacts with the α3 portion of the class I MHC molecule. CD8αβ is expressed on human peripheral T cells and functions as a coreceptor and can greatly increase the sensitivity and breadth of antigen recognition by CD8+ peripheral T cells bearing TCR.
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