目录产品 » Siglec-3/CD33, His, Cynomolgus
Siglec-3/CD33, His, Cynomolgus

The purity of Siglec-3/CD33, His, Cynomolgus is greater than 95% as determined by SEC-HPLC.

Siglec-3/CD33, His, Cynomolgus

Siglec-3/CD33, His, Cynomolgus on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Siglec-3/CD33, His, Cynomolgus

Sialic-acid-binding immunoglobulin-like lectin (Siglec) that plays a role in mediating cell-cell interactions and in maintaining immune cells in a resting state.They are sialoadhesin/CD169/Siglec-1, CD22/Siglec-2, CD33/Siglec-3, Myelin-Associated Glycoprotein (MAG/Siglec-4a) and Siglecs 5 to 11. To date, no Siglec has been shown to recognized any cell surface ligand other than sialic acids, suggesting that interactions with glycans containing this carbohydrate are important in mediating the biological functions of Siglecs.
Z04138
￥3500

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产品简介
Species Cynomolgus
Protein Construction
Siglec-3/CD33 (Ser17-Leu248)
Accession # XP_005590138.1		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 26.83 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 40-50 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

图例
  • Siglec-3/CD33, His, Cynomolgus
    • Siglec-3/CD33, His, Cynomolgus

    The purity of Siglec-3/CD33, His, Cynomolgus is greater than 95% as determined by SEC-HPLC.

  • Siglec-3/CD33, His, Cynomolgus
    • Siglec-3/CD33, His, Cynomolgus

    Siglec-3/CD33, His, Cynomolgus on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


技术背景
Target Background Sialic-acid-binding immunoglobulin-like lectin (Siglec) that plays a role in mediating cell-cell interactions and in maintaining immune cells in a resting state.They are sialoadhesin/CD169/Siglec-1, CD22/Siglec-2, CD33/Siglec-3, Myelin-Associated Glycoprotein (MAG/Siglec-4a) and Siglecs 5 to 11. To date, no Siglec has been shown to recognized any cell surface ligand other than sialic acids, suggesting that interactions with glycans containing this carbohydrate are important in mediating the biological functions of Siglecs.
Synonyms CD33 molecule; CD33; FLJ00391; gp67; Siglec3; Siglec-3; p67

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.


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