Immobilized Human CD30 Ligand, His Tag at 5 μg/ml (100 μL/well) on the plate. Dose response curve for CD30/TNFRSF8[Biotin], His & Avi, Human, His Tag with the EC50 of 17.5 ng/ml determined by ELISA.
The purity of CD30/TNFRSF8[Biotin], His & Avi, Human is greater than 95% as determined by SEC-HPLC.
CD30/TNFRSF8[Biotin], His & Avi, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
CD30/TNFRSF8[Biotin], His & Avi, Human
The transmembrane receptor CD30 (TNFRSF8) and its ligand CD30L (CD153, TNFSF8) are members of the tumor necrosis factor (TNF) superfamily and display restricted expression in subpopulations of activated T-and B-cells in nonpathologic conditions. CD30 expression is upregulated in various hematological malignancies, including Reed-Sternberg cells in Hodgkin's disease (HD), anaplastic large cell lymphoma (ALCL) and subsets of Non-Hodgkin's lymphomas (NHLs).
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