Immobilized VEGF R3/FLT4 hFc Chimera, Mouse at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Human VEGF-C, His Tag with the EC50 of 10.5 ng/ml determined by ELISA.

VEGF R3/FLT4 hFc Chimera, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of VEGF R3/FLT4 hFc Chimera, Mouse is greater than 95% as determined by SEC-HPLC.

VEGF R3/FLT4 hFc Chimera, Mouse

Vascular endothelial growth factor (VEGF) and its receptors VEGF-R1, -R2 and -R3 play important roles in tumor angiogenesis and are associated with poor prognosis in several solid tumors.VEGF-R1, -R2 and -R3 were highly expressed in CRC cells and stromal vessels. VEGF-R1 strong positive staining correlated with shorter survival after CRC surgery.

产品编号	Z03974
规格	100 μg 500 μg 大单询价
数量
价格	￥3400


联系我们

产品简介

Species

Mouse

Protein Construction

VEGF R3/FLT4 (Tyr25-Glu775) Accession # P35917	hFc
N-term	C-term

Purity

> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC

Endotoxin Level

Less than 1EU per μg by the LAL method.

Biological Activity

Immobilized VEGF R3/FLT4 hFc Chimera, Mouse (Cat.No.: Z03974) at 1 μg/ml (100μl/Well) on the plate can bind Human VEGF-C, His Tag

Expression System

HEK293

Theoretical Molecular Weight

111.69 kDa

Apparent Molecular Weight

Due to glycosylation, the protein migrates to 115-160 kDa based on Bis-Tris PAGE result.

Formulation

Lyophilized from a 0.22 μm filtered solution in PBS, (pH 7.4).

Reconstitution

It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH₂O more than 100 μg/ml.

Storage & Stability

Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

图例

Immobilized VEGF R3/FLT4 hFc Chimera, Mouse at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Human VEGF-C, His Tag with the EC50 of 10.5 ng/ml determined by ELISA.

VEGF R3/FLT4 hFc Chimera, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of VEGF R3/FLT4 hFc Chimera, Mouse is greater than 95% as determined by SEC-HPLC.

技术背景

Target Background	Vascular endothelial growth factor receptor 3 (VEGFR3) is one kind of tyrosine-protein kinase. VEGFR3 acts as a cell-surface receptor for VEGFC and VEGFD. It is a key regulator of lymphatic system development and establishment. VEGFR3 plays important roles in angiogenesis. It is also up-regulated in the endothelium of blood vessels in breast cancer and various other tumors.
Synonyms	VEGFR-3; FLT-4; LMPH1A; PCLFLT41; VEGFR3; FLT-41; PCL

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.