| ￥3400 | |
| Z03974-100 | |
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| Species | Mouse | ||||
| Protein Construction |
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| Purity |
> 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC |
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| Endotoxin Level | Less than 1EU per μg by the LAL method. | ||||
| Biological Activity | Immobilized VEGF R3/FLT4 hFc Chimera, Mouse (Cat.No.: Z03974) at 1 μg/ml (100μl/Well) on the plate can bind Human VEGF-C, His Tag | ||||
| Expression System | HEK293 | ||||
| Theoretical Molecular Weight | 111.69 kDa | ||||
| Apparent Molecular Weight | Due to glycosylation, the protein migrates to 115-160 kDa based on Bis-Tris PAGE result. | ||||
| Formulation | Lyophilized from a 0.22 μm filtered solution in PBS, (pH 7.4). | ||||
| Reconstitution | It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH2O more than 100 μg/ml. | ||||
| Storage & Stability | Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles. |
Immobilized VEGF R3/FLT4 hFc Chimera, Mouse at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Human VEGF-C, His Tag with the EC50 of 10.5 ng/ml determined by ELISA. »
VEGF R3/FLT4 hFc Chimera, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »
The purity of VEGF R3/FLT4 hFc Chimera, Mouse is greater than 95% as determined by SEC-HPLC. »
VEGF R3/FLT4 hFc Chimera, Mouse, hFc Tag captured on CM5 Chip via Protein A can bind Human VEGF-C, His Tag with an affinity constant of 12.93 pM as determined in SPR assay (Biacore T200). »
| Target Background | Vascular endothelial growth factor receptor 3 (VEGFR3) is one kind of tyrosine-protein kinase. VEGFR3 acts as a cell-surface receptor for VEGFC and VEGFD. It is a key regulator of lymphatic system development and establishment. VEGFR3 plays important roles in angiogenesis. It is also up-regulated in the endothelium of blood vessels in breast cancer and various other tumors. |
| Synonyms | VEGFR-3; FLT-4; LMPH1A; PCLFLT41; VEGFR3; FLT-41; PCL |
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.
