| Species |
Mouse |
| Protein Construction |
Her3/ErbB3 (Ser20-His641)
Accession # Q61526 |
His |
| N-term |
C-term |
|
| Purity |
> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC |
| Endotoxin Level |
Less than 1EU per μg by the LAL method. |
| Biological Activity |
Immobilized Her3/ErbB3, His, Mouse (Cat.No.: Z03910) at 2 μg/ml (100μl/Well) on the plate can bind Human NRG1 Beta 1, hFc Tag |
| Expression System |
HEK293 |
| Theoretical Molecular Weight |
69.59 kDa |
| Apparent Molecular Weight |
Due to glycosylation, the protein migrates to 78-100 kDa based on Bis-Tris PAGE result. |
| Formulation |
Lyophilized from a 0.22 μm filtered solution in PBS, pH 7.4. |
| Reconstitution |
It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH2O more than 100 μg/ml. |
| Storage & Stability |
Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.
-80°C for 3 months after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Her3/ErbB3, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Her3/ErbB3, His, Mouse is greater than 95% as determined by SEC-HPLC.
Immobilized Her3/ErbB3, His, Mouse at 2 μg/ml (100 μl/well) on the plate. Dose response curve for Human NRG1 Beta 1, hFc Tag with the EC50 of 57.7 ng/ml determined by ELISA.
| Target Background |
Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and Schwann cells. Monomeric Her3 serves as a low affinity receptor for the heregulins (HRG). |
| Synonyms |
ErbB3; ErbB-3; HER3; HER3c-erbB-3; LCCS2; MDA-BF-1; MGC88033; p180-ErbB3; p45-sErbB3; p85-sErbB3; ERBB3 |
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.
