Her3/ErbB3, His & Avi, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Her3/ErbB3, His & Avi, Human is greater than 95% as determined by SEC-HPLC.

Immobilized Her3/ErbB3, His & Avi, Human at 5 μg/ml (100 μl/well) on the plate. Dose response curve for Human NRG1 Beta 1, hFc Tag with the EC50 of 14.2 ng/ml determined by ELISA.

Her3/ErbB3, His & Avi, Human

Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors. Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and Schwann cells. Monomeric Her3 serves as a low affinity receptor for the heregulins (HRG).

产品编号	Z03905
规格	100 μg 500 μg 大单询价
数量
价格	￥1950


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产品简介

Species

Human

Protein Construction

Her3/ErbB3 (Ser20-Thr643) Accession # P21860-1	His	Avi
N-term		C-term

Purity

> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC

Endotoxin Level

Less than 1EU per μg by the LAL method.

Biological Activity

Immobilized Her3/ErbB3, His & Avi, Human (Cat.No.: Z03905) 5 μg/ml (100μl/well) on the plate can bind Human NRG1 Beta 1, hFc Tag

Expression System

HEK293

Theoretical Molecular Weight

71.6 kDa

Apparent Molecular Weight

Due to glycosylation, the protein migrates to 90-110 kDa based on Bis-Tris PAGE result.

Formulation

Lyophilized from a 0.22 μm filtered solution in PBS, pH 7.4.

Reconstitution

It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH₂O more than 100 μg/ml.

Storage & Stability

Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

图例

Her3/ErbB3, His & Avi, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Her3/ErbB3, His & Avi, Human is greater than 95% as determined by SEC-HPLC.

Immobilized Her3/ErbB3, His & Avi, Human at 5 μg/ml (100 μl/well) on the plate. Dose response curve for Human NRG1 Beta 1, hFc Tag with the EC50 of 14.2 ng/ml determined by ELISA.

技术背景

Target Background	Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors. Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and Schwann cells. Monomeric Her3 serves as a low affinity receptor for the heregulins (HRG).
Synonyms	ErbB3; ErbB-3; HER3; HER3c-erbB-3; LCCS2; MDA-BF-1; MGC88033; p180-ErbB3; p45-sErbB3; p85-sErbB3; ERBB3

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.