Her2/ErbB2[Biotin], His & Avi, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Her2/ErbB2[Biotin], His & Avi, Human is greater than 95% as determined by SEC-HPLC.

Immobilized Her2/ErbB2[Biotin], His & Avi, Human at 0.5 μg/ml (100 μl/Well) on streptavidin(5 μg/ml) precoated plate. Dose response curve for Anti-HER2 Antibody, hFc Tag with the EC50 of 2.2 ng/ml determined by ELISA.

Her2/ErbB2[Biotin], His & Avi, Human

ErbB2, also called Neu and Her2 (human epidermal growth factor receptor 2), is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors. ErbB family members serve as receptors for the epidermal growth factor (EGF) family of growth factors.Upon ERBB2 activation, the MEMO1-RHOA-DIAPH1 signaling pathway elicits the phosphorylation and thus the inhibition of GSK3B at cell membrane.

产品编号	Z03901
规格	100 μg 500 μg 大单询价
数量
价格	￥5700


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产品简介

Species

Human

Protein Construction

Her2/ErbB2 (Thr23-Thr652) Accession # P04626-1	His	Avi
N-term		C-term

Conjugate

Biotin

Purity

> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC

Endotoxin Level

Less than 1EU per μg by the LAL method.

Biological Activity

Immobilized Her2/ErbB2[Biotin], His & Avi, Human (Cat.No.: Z03901) at 0.5 μg/ml (100μl/Well) on the streptavidin precoated plate can bind Anti-HER2 Antibody, hFc Tag

Expression System

HEK293

Theoretical Molecular Weight

72.3 kDa

Apparent Molecular Weight

Due to glycosylation, the protein migrates to 80-100 kDa based on Bis-Tris PAGE result.

Formulation

Lyophilized from a 0.22 μm filtered solution in PBS, pH 7.4.

Reconstitution

It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH₂O more than 100 μg/ml.

Storage & Stability

Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

图例

Her2/ErbB2[Biotin], His & Avi, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Her2/ErbB2[Biotin], His & Avi, Human is greater than 95% as determined by SEC-HPLC.

技术背景

Target Background

Synonyms

CD340; EGFR2; ErbB2; HER2; HER-2; herstatin; MLN 19; MLN19; NGL; TKR1; ERBB2; NEU; ENV; ENVW; ERVWE1; HERV7Q; HERVW

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.

Her2/ErbB2[Biotin], His & Avi, Human

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