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FAP hFc Chimera, Human

Fibroblast activation protein (FAP) is a serine protease that has been reported in fibroblasts and some carcinoma cells, which correlates with poor patient outcomes. FAP can be induced under hypoxia which is also vital in the malignant behaviors of cancer cells.
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Z03893-100

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产品简介
Species Human
Protein Construction
hFc FAP (Leu26-Asp760 )
Accession # Q12884-1
N-term C-term
Purity > 90% as determined by Bis­-Tris PAGE
Endotoxin Level Less than 0.01 EU per μg by the LAL method
Biological Activity Measured by its binding ability in a functional ELISA.Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 112.3 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 110-­140 kDa based on Bis­Tris PAGE result.
Formulation Lyophilized from a 0.22 μm filtered solution in PBS, pH 7.4.
Reconstitution It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH2O more than 100 μg/ml.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.
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图例
FAP HFc Chimera, Human

The purity of FAP hFc Chimera, Human is greater than 90% as determined by SEC-HPLC. »

FAP HFc Chimera, Human

FAP hFc Chimera, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

FAP HFc Chimera, Human

Immobilized FAP hFc Chimera, Human at 2 μg/ml(100 μl/well) on the plate. Dose response curve for Biotinylated Anti-FAP Antibody, hFc Tag with the EC50 of 44.4 ng/ml determined by ELISA. »

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技术背景
Target Background Fibroblast activation protein (FAP) is a serine protease that has been reported in fibroblasts and some carcinoma cells, which correlates with poor patient outcomes. FAP can be induced under hypoxia which is also vital in the malignant behaviors of cancer cells.
Synonyms FAP; FAPalpha; SIMP; Seprase; APCE; DPPIV; DPPIVA; FAPA
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For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.