Species |
Human |
Protein Construction |
VEGFR2 (Ala20-Glu764) Accession # P35968-1 |
His tag |
Avi tag |
N-term |
|
C-term |
|
Purity |
> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC |
Endotoxin Level |
Less than 1 EU per μg by the LAL method. |
Biological Activity |
Immobilized VEGFR2, Avi & His, Human (Cat.No.: Z03811) at 0.5 μg/ml can bind AntiVEGFR2 Antibody. |
Expression System |
HEK293 |
Theoretical Molecular Weight |
86.2 kDa |
Apparent Molecular Weight |
Due to glycosylation, the protein migrates to 115-140 kDa based on Bis-Tris PAGE result. |
Formulation |
Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Storage & Stability |
Upon receiving, the lyophilized product remains stable up to 6 months at -20 °C or below as supplied from date of receipt.-80°C for 3 months after reconstitution.Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |

The purity of VEGFR2, Avi & His, Human is greater than 95% as determined by SEC-HPLC.

VEGFR2, Avi & His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Immobilized VEGFR2, Avi & His, Human at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-VEGF R2 Antibody, hFc Tag with the EC50 of 5.2 ng/ml determined by ELISA.
Target Background |
The kinase insert domain receptor (KDR), also known as vascular endothelial growth factor receptor 2 (VEGFR-2), is a type IV receptor tyrosine kinase that plays a crucial role in various biological processes, including embryonic vasculature development, angiogenesis regulation, cell survival, migration, macrophage function, chemotaxis, and cancer cell invasion. It acts as a cell-surface receptor for VEGFA, VEGFB, and PGF. The human gene encoding KDR is also known as CD309 and Flk1 (Fetal Liver Kinase 1). VEGFR2 is a key regulator of angiogenesis. |
Synonyms |
CD309; KDR; VEGFR; VEGFR2; VEGFR-21; FLK1; KRD1; Ly73 |
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.